In-vitro Synthesis of Gold Nanoclusters in Neurons

Report No. ARL-TN-0753
Authors: Maggie Gillan; Nicole Zander
Date/Pages: April 2016; 14 pages
Abstract: Gold nanoclusters (AuNCs) synthesized intracellularly have potential for use as in-vivo or in-vitro pressure probes for evaluating the effects of traumatic brain injury. AuNCs were grown within NG-108-15 neuroblastoma-glioma hybrid cells, indicated by increased fluorescence intensity at 488 nm. Effect of gold salt concentration on fluorescence intensity was evaluated. Cell viability at 24-h postgold salt addition was tested via an MTS cell viability assay.
Distribution: Approved for public release
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Last Update / Reviewed: April 1, 2016