Human Research Protection Program (HRPP)

Federal regulations (32 CFR 219 and DoDI 3216.02) require each institution that conducts or supports research involving human subjects must have a HRPP. Internal and external research involving human subjects must receive review and approval prior to initiating the project.

The primary mission of the U.S. Army Combat Capabilities Development Command Army Research Laboratory HRPP is to protect the safety, rights, and welfare of human subjects in research conducted under its purview. The HRPP ensures that all of CCDC ARL’s activities related to human subject research will be guided by the ethical principles set forth in the Belmont Report.

The ARL HRPP has a DOD assurance, #A10038, in accordance with applicable regulation. The Army Human Research Protection Office (AHRPO) provides oversight for the assurance.

  • HRPP Review Process
  • Frequently Asked Questions

Types of Reviews

Review by the CCDC ARL HRPP is required for all Human Subjects Research conducted by CCDC ARL investigators and when CCDC ARL provides support for research ($, facilities, equipment, CRADA, etc.).

Note for Collaborations: HRPOs are still required, even if CCDC ARL serves as the IRB of record. It is possible that the project is both an internal and external project.

Internal research conducted by CCDC ARL investigators must be reviewed by the CCDC ARL HRPP. Only an Exempt Determination Official from the CCDC ARL HRPP can determine if research is considered exempt. All non-exempt research is reviewed by the CCDC ARL Institutional Review Board (IRB) or a designated IRB member.

External research is any time CCDC ARL provides support for research (funding, facilities, equipment, CRADA, etc.) to a non-DoD institution. A Human Research Protection Official (HRPO) review is required for all external research. This includes review of exempt determinations. The HRPO review is a regulatory review only. It is not a secondary IRB review. Research may not begin until the study is approved by the HRPO.

Forms to Submit at Initial Review

If you have further questions, contact your program manager or the CCDC ARL HRPP office:
usarmy.apg.ccdc.mbx.arl-irb-office@mail.mil

References

Guiding Principles

Department of Defense Resources